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1X97:
Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat, 2S4S)
PDB ID:
1X97
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MMDB ID:
29788
PDB Deposition Date:
2004/8/19
Updated in MMDB:
2012/11
Experimental Method:
x-ray diffraction
Resolution:
1.4 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 1X97: monomeric; determined by author
Molecular Components in 1X97
Label
Count
Molecule
Protein (1 molecule)
A
1
Aldose Reductase
(Gene symbol:
AKR1B1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
(2R,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303